ABSTRACT
Background: Acute hyperglycaemia may predict a higher risk of hospitalization mortality after ischemic stroke in non-diabetic patients and a higher risk of poor functional improvement in non-diabetic stroke patients. It is thought that insula involvement in right cerebral hemispheres has a role in autonomic control of the heart. Troponin is a sensitive marker that is widely used in the diagnosis and risk stratification of acute coronary syndrome. High troponin I is found in acute stroke patients and is associated with a poorer prognosis.Methods: The study was cross-sectional, 30 patients diagnosed with acute ischemic stroke at Haji Adam Malik General Hospital Medan from June 16, 2017 to March 31, 2018. All participants were taken blood to measure blood glucose levels at the time of admission >140 mg/dL with a history of previous or not diabetes. Troponin I levels was checked when acute ischemic stroke patients had entered the inpatient room. The patient's prognosis is determined by National Institute of Health Stroke Scale (NIHSS) and Modified Rankin Scale (MRS). The calculation of NIHSS and MRS scores was performed on the first day of admission and the fourteenth day after being admitted to the hospital. Statistical test using Fisher exact test.Results: Of the 30 samples consisted of 19 men and 11 women. The significant effect between hyperglycaemia in acute ischemic stroke patients with diabetes and non-diabetes on the fourteenth day NIHSS (PR 2.8; 95% CI, 1.184-6,622; p=0.045).Conclusions: There was an effect between hyperglycaemia in non-diabetic and diabetic on the poor prognosis of acute ischemic stroke patients.
ABSTRACT
Background: Diabetes and higher HbA1c level have increased the incidence of stroke. Hemoglobin levels both high and low are associated with poor outcomes. Leukocytes play an important role in the initiation of the atherosclerosis process.Methods: This was a cross-sectional study with a sample size of 62 people selected by non-random sampling method on a consecutive basis, patients with acute stroke were taken blood to measure blood glucose levels, HbA1c, Hb and Leucocytes when entering the hospital room. Outcomes were assessed using NIHSS and MRS. The calculation of NIHSS and MRS scores was performed on the first day of admission and the fourteenth day. To analyze the correlation of blood sugar levels during HbA1c, Hb and leukocytes in acute stroke, this study used Spearman's correlation test. The p value <0.05 was considered statistically significant.Results: The study subjects of 62 acute stroke patients (acute ischemic stroke 31 people and 31 people hemorrhagic stroke). Acute stroke patients were consisted of 38 men (61.3%) and 24 women (38.7%). Of 31 people with hemorrhagic stroke, there were 16 men (51.6%) and 15 women (48.4%), ischemic stroke patients were consisted of 22 people (71, 0%) and women were 9 people. Spearrman repair test showed no symptoms between blood glucose levels, HbA1c, Hemoglobin and leukocytes with outcomes in acute stroke.Conclusions: There was no significant association between blood glucose levels, HbA1c, hemoglobin and leukocytes with outcomes in acute stroke.